Description

Methyl 2-(n- Phthalimidomethyl)-3-Oxobutyrate CAS NO 16880-35-6 is a specialized organic compound featuring a phthalimide-protected amino group and a β-ketoester moiety. This unique bifunctional structure makes it a valuable advanced pharmaceutical intermediate (API) and a versatile building block for complex organic synthesis. It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, particularly those requiring protected amine functionalities.
• Peptidomimetic Synthesis: Serves as a crucial building block for creating peptide analogs and mimetics in medicinal chemistry research.
• Heterocyclic Compound Production: Used in the construction of nitrogen-containing heterocycles, which are core structures in many pharmaceuticals and agrochemicals.
• Organic Synthesis Reagent: Acts as a versatile reagent for introducing specific molecular fragments in multi-step synthetic routes.
• Research & Development (R&D): Employed in academic and industrial R&D labs for exploring new chemical entities and reaction methodologies.
• Fine Chemical Manufacturing: Intermediate in the production of high-value, low-volume specialty chemicals for various industrial applications.

Basic Information

Product Name	Methyl 2-(n- Phthalimidomethyl)-3-Oxobutyrate
CAS No.	16880-35-6
Molecular Formula	C15H15NO5
Molecular Weight	289.28 g/mol
Synonyms	Methyl 2-(Phthalimidomethyl)-3-oxobutanoate; 3-Oxobutyric acid, 2-(phthalimidomethyl)-, methyl ester; Methyl 2-(phthalimidomethyl)acetoacetate; 2-(Phthalimidomethyl)-3-oxobutanoic acid methyl ester; N-(2-Methoxycarbonyl-3-oxobutyl)phthalimide; Acetoacetic acid, (phthalimidomethyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 2-(n- Phthalimidomethyl)-3-Oxobutyrate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting research and industrial grade specifications. A detailed Certificate of Analysis (COA) documenting all critical parameters is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.