Description

5-Isoxazolecarboxylicacid,3-Methoxy-,Methylester(8Ci,9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its functionalized isoxazole scaffold, which serves as a versatile precursor for constructing complex molecules with potential biological activity. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates. Its precise structure, identified by CAS NO 16880-11-8, makes it a critical component for medicinal chemistry programs and material science research.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the isoxazole moiety.
• Material Science: Serves as a precursor for functionalized polymers, liquid crystals, and organic electronic materials due to its aromatic heterocyclic structure.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or a tagging reagent in the design of chemical probes and activity-based protein profiling (ABPP) agents.
• Academic & Contract Research: Essential for methodological development in organic synthesis, including cycloaddition reactions and cross-coupling chemistry.
• Fine Chemical Synthesis: Intermediate for producing complex flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	5-Isoxazolecarboxylicacid,3-Methoxy-,Methylester(8Ci,9Ci)
CAS No.	16880-11-8
Molecular Formula	C6H7NO4
Molecular Weight	157.12 g/mol
Synonyms	Methyl 3-methoxy-1,2-oxazole-5-carboxylate; 3-Methoxyisoxazole-5-carboxylic Acid Methyl Ester; 5-Carbomethoxy-3-methoxyisoxazole; Methyl 3-methoxyisoxazole-5-carboxylate; 3-Methoxy-5-(methoxycarbonyl)isoxazole; 1,2-Oxazole-5-carboxylic acid, 3-methoxy-, methyl ester; 16880-11-8
EINECS	Contact for details

Quality Control

Our 5-Isoxazolecarboxylicacid,3-Methoxy-,Methylester(8Ci,9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistent performance for research and scale-up applications. Standard quality parameters include assay by HPLC, identity confirmation by IR and NMR spectroscopy, and control of related substances. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.