Description

(S)-2-Chlorooctane is a high-purity chiral building block and alkylating agent of significant importance in advanced organic synthesis. Its value lies in its ability to introduce a stereodefined octyl chain with a chlorine handle, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require enantiomerically pure intermediates for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the production of chiral pesticides, herbicides, and plant growth regulators where specific stereochemistry is crucial for bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of chiral liquid crystals, polymers, and other advanced functional materials.
• Organic Methodology Development: A valuable substrate for testing new asymmetric alkylation and substitution reactions in academic and industrial R&D.
• Flavor and Fragrance Industry: Potential intermediate for the synthesis of stereochemically defined aroma compounds.

Basic Information

Product Name	(S)-2-Chlorooctane
CAS No.	16844-08-9
Molecular Formula	C8H17Cl
Molecular Weight	148.67 g/mol
Synonyms	(S)-2-Chlorooctane; (S)-(-)-2-Chlorooctane; (S)-1-Chloro-2-methylheptane; (2S)-2-Chlorooctane; (+)-(S)-2-Chlorooctane; sec-Octyl chloride, (S)-; 2-Chlorooctane, (S)-; Octane, 2-chloro-, (2S)-
EINECS	240-870-9

Quality Control

Our (S)-2-Chlorooctane is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. We provide comprehensive analytical data, including Chiral HPLC for enantiomeric excess (ee) verification and GC for chemical purity assessment. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and active metals. Recommended storage temperature is 2-8°C for long-term stability. The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Specific Rotation [α]	Contact for details
Refractive Index (n20/D)	Contact for details
Density (g/mL, 20°C)	Contact for details
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.