Description

(E)-3,4,4-Trimethyl-2-Pentenoic Acid Ethyl Ester CAS NO 16812-82-1 is a high-purity, unsaturated ester building block with a defined stereochemistry. This compound is valued for its role as a versatile intermediate in the synthesis of complex organic molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by R&D chemists and process development teams for constructing specific molecular architectures. The defined (E)-configuration ensures consistent reactivity and predictable outcomes in synthetic pathways.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring specific olefin geometry.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators where the trimethyl-substituted pentenoate moiety is integral.
• Flavor & Fragrance Ingredient: Serves as a precursor for musky or fruity aroma compounds, leveraging its ester functionality and branched carbon chain.
• Organic Synthesis Building Block: Employed in academic and industrial research for Diels-Alder reactions, Michael additions, and other carbon-carbon bond-forming transformations.
• Material Science Monomer: Investigated for use in specialty polymerizations to introduce specific side-chain functionalities into polymeric materials.
• Chemical Research Standard: Used as an analytical reference standard for method development and quality control in chemical manufacturing.

Basic Information

Product Name	(E)-3,4,4-Trimethyl-2-Pentenoic Acid Ethyl Ester
CAS No.	16812-82-1
Molecular Formula	C10H18O2
Molecular Weight	170.25 g/mol
Synonyms	Ethyl (E)-3,4,4-Trimethyl-2-pentenoate; (E)-Ethyl 3,4,4-Trimethylpent-2-enoate; 2-Pentenoic Acid, 3,4,4-Trimethyl-, Ethyl Ester, (E)-; trans-3,4,4-Trimethyl-2-pentenoic Acid Ethyl Ester; Ethyl trans-3,4,4-Trimethyl-2-pentenoate; 3,4,4-Trimethyl-2-pentenoic Acid Ethyl Ester; NSC 163022
EINECS	Contact for details

Quality Control

Our (E)-3,4,4-Trimethyl-2-Pentenoic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and stereochemical confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Isomeric Purity ((E)-isomer)	≥ 98.0% (by GC/HPLC)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.