Description

3-Chloro-8-Methoxyquinolin-4-Ol is a versatile quinoline derivative that serves as a crucial synthetic intermediate and building block in advanced organic chemistry. Its unique halogenated and methoxylated structure makes it a valuable precursor for the development of complex molecules with targeted biological and material properties. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for applications ranging from drug discovery to the synthesis of functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds with potential antimicrobial, anticancer, or anti-inflammatory properties.
• Agrochemical Research: Used in the development and production of advanced pesticides, herbicides, and fungicides, leveraging its heterocyclic core for bioactivity.
• Organic Synthesis Reagent: Serves as a versatile precursor for metal-catalyzed cross-coupling reactions, nucleophilic substitutions, and the construction of complex polycyclic systems in research and development.
• Material Science: Employed in the synthesis of organic ligands for metal-organic frameworks (MOFs), catalysts, and specialty polymers requiring specific quinoline-based architectures.
• Dye and Pigment Industry: Acts as an intermediate for the production of specialized quinoline-based dyes and colorants.
• Analytical Chemistry: May be used as a standard or reference compound in chromatographic analysis and method development.

Basic Information

Product Name	3-Chloro-8-Methoxyquinolin-4-Ol
CAS No.	16778-22-6
Molecular Formula	C₁₀H₈ClNO₂
Molecular Weight	209.63 g/mol
Synonyms	4-Hydroxy-3-chloro-8-methoxyquinoline; 8-Methoxy-3-chloroquinolin-4-ol; 3-Chloro-8-methoxy-4-quinolinol; 3-Chloro-8-methoxy-4-hydroxyquinoline; 4-Quinolinol, 3-chloro-8-methoxy-; 3-Chloro-8-methoxyquinolin-4-ol; Quinoline derivative, 3-chloro-8-methoxy-4-ol
EINECS	Contact for details

Quality Control

Our 3-Chloro-8-Methoxyquinolin-4-Ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive quality assurance, with products typically meeting a purity specification of ≥97% (by HPLC). A detailed Certificate of Analysis (COA) is supplied with each batch, documenting identity, purity, and impurity profiles. Our quality control protocols are designed to support cGMP and ISO standards for reliable sourcing in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.