Description

tert-Butyl 3-Bromo-2-oxopropanoate is a high-purity brominated ketoester building block essential for advanced organic synthesis. This compound is valued for its reactive bromine and ketone functionalities, enabling efficient construction of complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those requiring functionalized α-ketoester frameworks.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Peptidomimetics Research: Serves as a valuable building block for creating peptide analogs and protease inhibitors.
• Material Science: Employed in the synthesis of specialized monomers and polymers with tailored properties.
• Cross-Coupling Reactions: Acts as an electrophilic partner in various palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes for studying enzyme function.

Basic Information

Product Name	tert-Butyl 3-Bromo-2-oxopropanoate
CAS No.	16754-73-7
Molecular Formula	C7H11BrO3
Molecular Weight	223.06 g/mol
Synonyms	3-Bromo-2-oxopropanoic acid tert-butyl ester; tert-Butyl bromopyruvate; 2-Oxopropyl bromoacetate tert-butyl ester; Bromopyruvic acid tert-butyl ester; tert-Butyl α-bromopyruvate; Bromopyruvic acid t-butyl ester; t-Butyl 3-bromo-2-oxopropanoate; 3-Bromo-2-oxo-propionic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Bromo-2-oxopropanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.