Description

Acetobromofucose CAS NO 16741-27-8 is a specialized glycosyl halide derivative, a crucial building block in synthetic carbohydrate chemistry. Its primary value lies in enabling the stereoselective synthesis of complex oligosaccharides and glycoconjugates, which are essential for biological research and pharmaceutical development. This high-purity intermediate is indispensable for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors working on glycomics, vaccine development, and novel therapeutic agents.

Application

• Glycosylation Reagent: A key donor molecule for the stereocontrolled chemical synthesis of fucose-containing oligosaccharides and glycans.
• Pharmaceutical Intermediate: Used in the research and production of glycan-based drugs, including selectin inhibitors and cancer therapeutics.
• Glycoconjugate Synthesis: Essential for creating defined glycoproteins, glycolipids, and neoglycoconjugates for immunological studies and diagnostic tools.
• Biochemical Probe Development: Serves as a precursor for labeled fucose analogs used to study fucosylation pathways and cell surface dynamics.
• Enzymatic Substrate Preparation: Used to prepare substrates for fucosyltransferase assays and enzyme characterization.
• Carbohydrate Library Construction: A critical component in combinatorial chemistry for generating diverse carbohydrate libraries for drug screening.

Basic Information

Product Name	Acetobromofucose
CAS No.	16741-27-8
Molecular Formula	C14H21BrO9
Molecular Weight	413.22 g/mol
Synonyms	2,3,4-Tri-O-acetyl-α-L-fucopyranosyl bromide; α-L-Fucopyranosyl bromide, 2,3,4-triacetate; 1-Bromo-2,3,4-tri-O-acetyl-α-L-fucopyranose; Tri-O-acetyl-α-L-fucopyranosyl bromide; Acetobromo-α-L-fucose; L-Fucose, 1-bromo-2,3,4-triacetate; 1-Bromo-1-deoxy-2,3,4-tri-O-acetyl-α-L-fucopyranose
EINECS	Contact for details

Quality Control

Our Acetobromofucose is manufactured under strict quality control protocols to ensure high chemical purity and batch-to-batch consistency, suitable for demanding synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality system is designed to meet the stringent requirements of research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Store away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.