Description

Silane, [[3,7-Dimethyl-9-(2,6,6-Trimethyl-1-Cyclohexen-1-Yl)-2,4,6,8-N Onatetraenyl]Oxy]Trimethyl-, All-(E)- is a specialized organosilicon derivative of vitamin A (retinol), designed for advanced surface modification and controlled release applications. This compound matters for its unique ability to act as a silane coupling agent with inherent biological activity, enabling the covalent attachment of retinoid-like molecules to inorganic substrates like glass, silica, or metals. It is primarily needed by R&D and production teams in the advanced materials, biomedical engineering, and specialty chemical synthesis sectors seeking to create bioactive coatings or functionalized delivery systems.

Application

• Surface Functionalization: Covalent grafting onto glass, silicon wafers, or metal oxides to create bioactive surfaces for cell culture or biosensing.
• Biomedical Coatings: Development of advanced coatings for medical devices or implants where localized retinoid activity is desired.
• Controlled Release Matrices: Incorporation into sol-gel or polymer matrices for the sustained release of vitamin A analogs.
• Specialty Polymer Synthesis: Serving as a functional monomer or cross-linker in the synthesis of silicon-containing polymers with specific optical or biological properties.
• Advanced Material Research: Key reagent in R&D for creating novel hybrid organic-inorganic materials with tailored surface energy and reactivity.
• Cosmetic Ingredient Intermediate: Potential use in the synthesis of novel, stabilized retinyl compounds for high-end cosmetic formulations.

Basic Information

Product Name	Silane, [[3,7-Dimethyl-9-(2,6,6-Trimethyl-1-Cyclohexen-1-Yl)-2,4,6,8-N Onatetraenyl]Oxy]Trimethyl-, All-(E)-
CAS No.	16729-17-2
Molecular Formula	C26H42O2Si
Molecular Weight	414.70 g/mol
Synonyms	Retinyloxytrimethylsilane; All-trans-Retinyl Trimethylsilyl Ether; Vitamin A Trimethylsilyl Ether; Trimethyl((all-trans-retinyl)oxy)silane; (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-yloxytrimethylsilane; Retinol TMS ether; TMS-Retinol; Retinyl TMS
EINECS	Contact for details

Quality Control

Our production of this high-value specialty chemical adheres to strict in-process controls to ensure batch-to-batch consistency and purity. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and GC-MS. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and isomer specification. We support cGMP and ISO 9001 aligned practices for traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive and light-sensitive nature. Allow the sealed container to reach ambient temperature before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	Yellow to orange viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC, Area %)	≥ 95.0% (All-(E) isomer)
Isomeric Purity (All-(E))	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.