Description

[(4-Methylphenyl)Amino]Acetonitrile is a versatile aromatic nitrile intermediate of significant importance in advanced organic synthesis. Its core value lies in providing a reactive nitrile group adjacent to a secondary amine, enabling its use as a key building block for constructing complex heterocyclic and pharmaceutical scaffolds. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates, particularly those containing indole, quinazoline, or other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where its structural motif can contribute to biological activity.
• Dye and Pigment Manufacturing: Serves as a building block for synthesizing complex organic dyes, pigments, and optical brighteners.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal catalysis and coordination chemistry applications.
• Polymer Chemistry: Acts as a monomer or modifier in the synthesis of specialty polymers with specific thermal or mechanical properties.
• Chemical Research & Development: A valuable reagent for methodological studies and constructing molecular libraries in medicinal and combinatorial chemistry.

Basic Information

Product Name	[(4-Methylphenyl)Amino]Acetonitrile
CAS No.	16728-84-0
Molecular Formula	C9H10N2
Molecular Weight	146.19 g/mol
Synonyms	2-[(4-Methylphenyl)amino]acetonitrile; N-(4-Methylphenyl)glycinonitrile; p-Tolylaminoacetonitrile; 4-Methylphenylaminoacetonitrile; (p-Tolylamino)acetonitrile; Glycinonitrile, N-(4-methylphenyl)-; Amino(4-methylphenyl)acetonitrile
EINECS	240-783-7

Quality Control

Our [(4-Methylphenyl)Amino]Acetonitrile is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of our global B2B clients. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to ensure full traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.