Description

Pyrrolo[2,1-B]Quinazolin-9(1H)-One, 3-[2-(Dimethylamino)Phenyl]-2,3-Dihydro-3-Hydroxy-5-Methoxy- is a complex heterocyclic organic compound of significant interest in advanced chemical synthesis. This molecule serves as a critical pharmacophore and synthetic intermediate for the development of novel bioactive compounds. It is primarily sought by pharmaceutical R&D teams, academic research institutions, and specialty chemical manufacturers engaged in creating new therapeutic agents and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex polycyclic nitrogen-containing heterocycles.
• Biochemical Research: Potential use as a tool compound or probe in biological assays to study enzyme inhibition or receptor binding.
• Fine Chemical Production: Intermediate in the manufacture of specialty dyes, pigments, or advanced materials with specific optical properties.

Basic Information

Product Name	Pyrrolo[2,1-B]Quinazolin-9(1H)-One, 3-[2-(Dimethylamino)Phenyl]-2,3-Dihydro-3-Hydroxy-5-Methoxy-
CAS No.	16688-21-4
Molecular Formula	C20H21N3O3
Molecular Weight	351.40 g/mol
Synonyms	3-[2-(Dimethylamino)phenyl]-2,3-dihydro-3-hydroxy-5-methoxy-1H-pyrrolo[2,1-b]quinazolin-9-one; 5-Methoxy-3-[2-(dimethylamino)phenyl]-2,3-dihydro-3-hydroxy-1H-pyrrolo[2,1-b]quinazolin-9-one; 16688-21-4; Pyrroloquinazolinone derivative; DMAP-substituted pyrroloquinazolinone
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure consistency and identity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP compliance for applications requiring the highest material standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.