Description

(2-Ethoxyethoxy)Trimethylsilane is a versatile organosilicon compound, specifically a silyl ether, valued for its role as a protective agent and chemical intermediate. Its primary commercial significance lies in its ability to introduce the (2-ethoxyethoxy)trimethylsilyl protecting group, which is crucial for safeguarding reactive functional groups during complex synthetic sequences. This product is essential for manufacturers and researchers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for advanced synthesis.

Application

• Protecting Group Reagent: Used in organic synthesis to protect hydroxyl groups in alcohols, phenols, and carbohydrates, particularly where selective deprotection is needed.
• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of active pharmaceutical ingredients (APIs) and complex drug molecules.
• Agrochemical Synthesis: Employed in the production of advanced pesticides, herbicides, and plant growth regulators requiring selective functional group manipulation.
• Surface Modification Agent: Used to functionalize silica, glass, and other inorganic surfaces to alter their hydrophobicity and reactivity.
• Silylation Agent in Chromatography: Acts as a derivatization reagent for gas chromatography (GC) to improve the volatility and detection of polar compounds.
• Precursor for Silicone Chemistry: Functions as a monomer or cross-linking agent in the synthesis of specialty silicone polymers and resins.

Basic Information

Product Name	(2-Ethoxyethoxy)Trimethylsilane
CAS No.	16654-45-8
Molecular Formula	C9H22O2Si
Molecular Weight	190.36 g/mol
Synonyms	2-(Trimethylsilyloxy)ethyl ethyl ether; Ethyl 2-(trimethylsilyloxy)ethyl ether; 1-Ethoxy-2-(trimethylsiloxy)ethane; (β-Ethoxyethoxy)trimethylsilane; Trimethyl[2-(ethoxy)ethoxy]silane; 2-Ethoxyethoxymethylsilane; EE-TMS; TMS-EE
EINECS	240-698-9

Quality Control

Our (2-Ethoxyethoxy)Trimethylsilane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Refractive Index (n20D)	1.405 - 1.410
Density (20°C)	0.86 - 0.90 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.