Description

(Triphenylphosphoranylidene)Acetonitrile is a versatile Wittig-type reagent and a key building block in organic synthesis. Its primary value lies in its ability to act as a stabilized ylide for the efficient synthesis of α,β-unsaturated nitriles, which are crucial intermediates in pharmaceuticals and advanced materials. This compound is essential for R&D chemists and process development scientists working in pharmaceutical, agrochemical, and specialty chemical manufacturing.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for constructing acrylonitrile moieties found in active pharmaceutical ingredients (APIs).
• Agrochemical Production: Used in the synthesis of herbicides, fungicides, and plant growth regulators containing nitrile functional groups.
• Material Science: Building block for polymers, liquid crystals, and organic electronic materials requiring conjugated nitrile systems.
• Organic Synthesis Research: A fundamental reagent for Horner-Wadsworth-Emmons (HWE) olefination reactions in academic and industrial R&D laboratories.
• Fine Chemical Manufacturing: Production of dyes, pigments, and complex fragrance molecules.

Basic Information

Product Name	(Triphenylphosphoranylidene)Acetonitrile
CAS No.	16640-68-9
Molecular Formula	C20H16NP
Molecular Weight	301.32 g/mol
Synonyms	2-(Triphenylphosphoranylidene)acetonitrile; (Cyanomethylene)triphenylphosphorane; Acetonitrile, (triphenylphosphoranylidene)-; Triphenylphosphonium acetonitrile ylide; Phosphorane, (cyanomethylene)triphenyl-; HWE Reagent for Acrylonitrile; Wittig Reagent for Nitriles
EINECS	240-698-1

Quality Control

Our (Triphenylphosphoranylidene)Acetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and elemental analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	178 - 182 °C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.