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Rac-(1R,2R)-2-(3-Chlorophenyl)Cyclopropane-1-Carboxylic Acid CAS NO 16633-45-7


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CAS No.:16633-45-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Rac-(1R,2R)-2-(3-Chlorophenyl)Cyclopropane-1-Carboxylic Acid is a high-purity chiral cyclopropane derivative, a crucial advanced intermediate in modern synthetic chemistry. Its value lies in its versatile cyclopropane ring structure, which serves as a key building block for constructing complex molecules with enhanced biological activity and stability. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

  • Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
  • Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the cyclopropane moiety can impart improved metabolic stability and efficacy.
  • Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
  • Material Science Research: Investigated as a monomer or additive for creating polymers with unique thermal and mechanical properties.
  • Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
  • Fine Chemical Production: Employed in custom synthesis and contract manufacturing for specialty and performance chemicals.

Basic Information

Product Name Rac-(1R,2R)-2-(3-Chlorophenyl)Cyclopropane-1-Carboxylic Acid
CAS No. 16633-45-7
Molecular Formula C10H9ClO2
Molecular Weight 196.63 g/mol
Synonyms (±)-trans-2-(3-Chlorophenyl)cyclopropanecarboxylic Acid; rac-(1R,2R)-rel-2-(3-Chlorophenyl)cyclopropanecarboxylic Acid; 2-(3-Chlorophenyl)cyclopropanecarboxylic Acid (racemic trans); DL-trans-2-(m-Chlorophenyl)cyclopropanecarboxylic Acid; 3-Chlorophenylcyclopropanecarboxylic Acid; NSC 334365; (1R*,2R*)-2-(3-Chlorophenyl)cyclopropane-1-carboxylic Acid
EINECS Contact for details

Quality Control

Our production of Rac-(1R,2R)-2-(3-Chlorophenyl)Cyclopropane-1-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is manufactured and tested in facilities that implement cGMP principles where applicable. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment, and we support customer audits and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals < 10 ppm
Specific Rotation Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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