Description

2-Chloro-5-Nitrobenzonitrile is a versatile aromatic nitrile building block characterized by its chloro and nitro substituents, which create distinct reactivity sites for further chemical synthesis. This compound matters as a critical intermediate for constructing complex molecules in advanced research and industrial manufacturing. It is primarily needed by the pharmaceutical and agrochemical industries for the development of active ingredients, as well as by research institutions and fine chemical producers engaged in organic synthesis and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with heterocyclic or complex aromatic structures.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where its functional groups allow for the introduction of specific biological activity.
• Organic Synthesis Building Block: Serves as a versatile starting material for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic aromatic substitution reactions.
• Dye and Pigment Manufacturing: Employed in the synthesis of specialized azo dyes and organic pigments due to its nitro and cyano groups.
• Material Science Research: Investigated as a monomer or additive for the development of advanced polymers and liquid crystals.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Product Name	2-Chloro-5-Nitrobenzonitrile
CAS No.	16588-02-6
Molecular Formula	C7H3ClN2O2
Molecular Weight	182.56 g/mol
Synonyms	5-Nitro-2-chlorobenzonitrile; 2-Chloro-5-nitrobenzenecarbonitrile; Benzonitrile, 2-chloro-5-nitro-; 2-Chloro-5-cyanomitrobenzene; 2-Chloro-5-nitro-phenyl cyanide; NSC 403119; 2-Chloro-5-nitrobenzonitril; 2-Chloro-5-nitro-benzonitril
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Nitrobenzonitrile is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We are committed to meeting the stringent requirements of cGMP and ISO standards for our pharmaceutical and industrial customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This product is light-sensitive (store away from light) and should be handled in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	145 - 149 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.