Description

(25R)-3β-Amino-5α-Spirostan-9-Ol CAS NO 16577-35-8 is a high-purity, steroidal alkaloid derivative belonging to the spirostan class, characterized by its specific amino and hydroxyl functional groups. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in synthetic organic chemistry. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for the development of novel therapeutic agents and bioactive molecules.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of steroidal drugs and bioactive compounds.
• Research & Development: Used in academic and industrial R&D for studying structure-activity relationships (SAR) and developing new chemical entities.
• Biochemical Research: Serves as a reference standard or reagent in biochemical assays and metabolic pathway studies.
• Fine Chemical Synthesis: A versatile chiral building block for constructing complex molecular architectures in asymmetric synthesis.
• API Development: Potential intermediate in the development of Active Pharmaceutical Ingredients (APIs) targeting various therapeutic areas.

Basic Information

Product Name	(25R)-3β-Amino-5α-Spirostan-9-Ol
CAS No.	16577-35-8
Molecular Formula	C27H45NO3
Molecular Weight	431.66 g/mol
Synonyms	(25R)-3β-Amino-5α-spirostan-9-ol; 9-Hydroxy-3β-amino-5α-spirostane; 3β-Amino-5α-spirostan-9-ol; (3β,5α,9ξ,25R)-Spirostan-3-amine-9-ol; 16577-35-8; 3-Amino-9-hydroxy-5α-spirostane; 3β-Amino-9-hydroxy-5α-spirostane
EINECS	Contact for details

Quality Control

Our (25R)-3β-Amino-5α-Spirostan-9-Ol is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored in original packaging away from direct light and moisture sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.