Description

4-Bromophenylacetonitrile is a versatile brominated aromatic nitrile compound that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a reactive nitrile group and a bromine substituent, makes it an indispensable intermediate for constructing complex molecules. This high-purity intermediate is primarily sought after by the pharmaceutical, agrochemical, and material science research sectors for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), including potential kinase inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where the bromophenyl moiety is required.
• Liquid Crystal & OLED Material Development: Serves as a starting material for creating advanced functional materials used in electronic displays and optoelectronic devices.
• Ligand & Catalyst Preparation: Employed in the synthesis of specialized ligands for metal-catalyzed cross-coupling reactions, such as Suzuki and Heck reactions.
• Dye & Pigment Manufacturing: Intermediate for producing specialized dyes and pigments with specific colorfastness and stability properties.
• Polymer Modification: Used to introduce bromine and nitrile functional groups into polymer backbones to alter physical and chemical properties.

Basic Information

Product Name	4-Bromophenylacetonitrile
CAS No.	16532-79-9
Molecular Formula	C8H6BrN
Molecular Weight	196.04 g/mol
Synonyms	(4-Bromophenyl)acetonitrile; p-Bromophenylacetonitrile; 2-(4-Bromophenyl)acetonitrile; 4-Bromobenzyl cyanide; (p-Bromophenyl)acetonitrile; α-Cyano-4-bromotoluene; 4-Bromo-α-tolunitrile; 4-Bromobenzeneacetonitrile
EINECS	240-624-3

Quality Control

Our 4-Bromophenylacetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. The container should be kept tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.