Description

7-Fluoro-4-Quinazolone is a high-value fluorinated heterocyclic building block, a key intermediate in modern pharmaceutical synthesis. Its core quinazolone scaffold, functionalized with a fluorine atom, is prized for its ability to modulate the biological activity and pharmacokinetic properties of drug candidates. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on kinase inhibitors, anticancer agents, and other biologically active small molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially kinase inhibitors and targeted cancer therapies.
• Agrochemical Research: Used in the development of new herbicides and pesticides, where the fluorine atom enhances bioactivity and environmental stability.
• Chemical Biology Probe Synthesis: Serves as a scaffold for creating molecular probes to study enzyme function and cellular pathways.
• Material Science Research: Investigated as a building block for advanced organic electronic materials and fluorescent dyes.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clients.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic and fluorine chemistry.

Basic Information

Product Name	7-Fluoro-4-Quinazolone
CAS No.	16499-57-3
Molecular Formula	C8H5FN2O
Molecular Weight	164.14 g/mol
Synonyms	7-Fluoroquinazolin-4(3H)-one; 7-Fluoro-4(3H)-quinazolinone; 4-Quinazolinone, 7-fluoro-; 7-Fluoro-3,4-dihydro-4-quinazolinone; 7-Fluoro-4-hydroxyquinazoline; 16499-57-3; 7-Fluoro-4-oxo-3,4-dihydroquinazoline
EINECS	Contact for details

Quality Control

Our 7-Fluoro-4-Quinazolone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.