Description

(1R,3Aβ,6Aβ)-1α,4α-Bis(3,4-Dimethoxyphenyl)Tetrahydro-1H,3H-Furo[3,4-C]Furan is a complex, chiral furofuran lignan derivative, a class of compounds known for their significant biological activity. This compound serves as a critical advanced pharmaceutical intermediate and a valuable scaffold for medicinal chemistry research. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents, particularly in the areas of oncology and neurology.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities targeting various diseases.
• Reference Standard: Used as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Biochemical Research: Investigated for its potential biological activities, which are characteristic of lignan derivatives, including antioxidant and enzyme inhibition properties.
• Asymmetric Synthesis: Employed in chiral synthesis due to its defined stereochemistry, aiding in the production of enantiomerically pure compounds.

Basic Information

Product Name	(1R,3Aβ,6Aβ)-1α,4α-Bis(3,4-Dimethoxyphenyl)Tetrahydro-1H,3H-Furo[3,4-C]Furan
CAS No.	16499-02-8
Molecular Formula	C22H26O6
Molecular Weight	386.44 g/mol
Synonyms	1α,4α-Bis(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan; (-)-Galbelgin; Galbelgin; (1R,3aS,6aR)-1,4-Bis(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan; Furo[3,4-c]furan, 1,4-bis(3,4-dimethoxyphenyl)tetrahydro-, (1R,3aS,6aR)-; Lignan Furofuran Derivative
EINECS	Contact for details

Quality Control

Our (1R,3Aβ,6Aβ)-1α,4α-Bis(3,4-Dimethoxyphenyl)Tetrahydro-1H,3H-Furo[3,4-C]Furan is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity, to ensure it meets the high standards required for pharmaceutical research. Comprehensive Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.