Description

2,3,4-Triiodo-5-Methylthiophene is a highly functionalized, multi-iodinated heterocyclic compound that serves as a critical synthetic intermediate. Its value lies in its ability to act as a versatile building block for complex molecular architectures, particularly in advanced material science and pharmaceutical research. This compound is essential for R&D chemists and manufacturers in the agrochemical, pharmaceutical, and organic electronics sectors who require precise, high-purity intermediates for coupling reactions and the synthesis of specialized ligands.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially those targeting thyroid hormone analogs or requiring heavy atom incorporation for X-ray crystallography.
• Agrochemical Synthesis: Used in the development of new-generation pesticides and herbicides, where the iodine atoms facilitate further functionalization to create bioactive molecules.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of conductive polymers and organic semiconductors for electronic devices.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) due to the high reactivity of the iodine substituents.
• Ligand Preparation: Useful for synthesizing specialized ligands for catalysis or metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A valuable reagent for exploratory chemistry in universities and corporate research laboratories focusing on heterocyclic and organoiodine chemistry.

Basic Information

Product Name	2,3,4-Triiodo-5-Methylthiophene
CAS No.	16494-47-6
Molecular Formula	C5H3I3S
Molecular Weight	507.85 g/mol
Synonyms	5-Methyl-2,3,4-triiodothiophene; 2,3,4-Triiodo-5-methylthiophene; Thiophene, 2,3,4-triiodo-5-methyl-; 5-Methylthiophene-2,3,4-triyl triiodide; Triiodomethylthiophene
EINECS	Contact for details

Quality Control

Every batch of 2,3,4-Triiodo-5-Methylthiophene is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards, and our comprehensive quality control includes identity confirmation, purity assay, and impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature, the container should be opaque or kept in dark conditions. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.