Description

3-Amino-4-Bromopyrazole is a versatile brominated heterocyclic building block of significant importance in modern synthetic chemistry. Its unique structure, featuring both an amino and a bromo substituent on the pyrazole core, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including kinase inhibitors and other biologically relevant heterocycles.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Potential precursor for the development of specialty polymers, ligands, and functional materials.
• Cross-Coupling Reactions: The bromo substituent makes it a suitable substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig amination.
• Heterocyclic Chemistry: Fundamental starting material for the elaboration of more complex fused or polycyclic heterocyclic systems.

Basic Information

Product Name	3-Amino-4-Bromopyrazole
CAS No.	16461-94-2
Molecular Formula	C3H4BrN3
Molecular Weight	161.99 g/mol
Synonyms	4-Bromo-1H-pyrazol-3-amine; 4-Bromo-3-aminopyrazole; 4-Bromo-1H-pyrazol-5-amine; 3-Amino-4-bromo-1H-pyrazole; 4-Bromopyrazol-3-ylamine; 1H-Pyrazol-3-amine, 4-bromo-
EINECS	Contact for details

Quality Control

Our 3-Amino-4-Bromopyrazole is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.