Description

(4Alpha,4Aalpha,8Aalpha)-Octahydro-4,8A-Dimethyl-4A(2H)-Naphthol is a high-purity, stereochemically defined decalin derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and valuable chiral building block for the construction of complex molecular architectures. It is particularly sought after by research and development teams in the pharmaceutical and fine chemical industries for applications in asymmetric synthesis, fragrance development, and materials science.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of bioactive molecules, including steroids and terpenoid-based therapeutics.
• Fragrance & Flavor Chemistry: Used as a precursor for the development of novel, complex woody, amber, and musk odorants with high stability.
• Asymmetric Catalysis: Employed as a ligand precursor or a chiral scaffold in the design of catalysts for enantioselective transformations.
• Advanced Material Research: Serves as a rigid, polycyclic core structure for the development of liquid crystals, organic semiconductors, and specialty polymers.
• Organic Synthesis Reference Standard: Used as a high-purity standard for analytical method development and quality control in chemical production.
• Academic & Industrial R&D: A valuable reagent for methodological studies in synthetic organic chemistry, particularly in hydrogenation and rearrangement reactions.

Basic Information

Product Name	(4Alpha,4Aalpha,8Aalpha)-Octahydro-4,8A-Dimethyl-4A(2H)-Naphthol
CAS No.	16452-32-7
Molecular Formula	C12H22O
Molecular Weight	182.30 g/mol
Synonyms	4α,4aα,8aα-Octahydro-4,8a-dimethyl-4a(2H)-naphthalenol; 4,8a-Dimethyl-decahydro-2-naphthol; 4a(2H)-Naphthalenol, octahydro-4,8a-dimethyl-, (4α,4aα,8aα)-; 4,8a-Dimethylperhydronaphthalen-2-ol; Decahydro-4,8a-dimethyl-2-naphthol; (4α,4aα,8aα)-4,8a-Dimethyl-decahydro-2-naphthol; 2-Naphthol, decahydro-4,8a-dimethyl-; 4,8a-Dimethyl-trans-decahydro-2-naphthol
EINECS	Contact for details

Quality Control

Our (4Alpha,4Aalpha,8Aalpha)-Octahydro-4,8A-Dimethyl-4A(2H)-Naphthol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by GC or HPLC, to ensure high chemical and isomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (GC/HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.