Description

(2-Phenyl-1,3-thiazol-4-yl)acetonitrile is a versatile heterocyclic nitrile building block of significant interest in advanced organic synthesis. Its core structure, featuring a phenyl-substituted thiazole ring linked to an acetonitrile group, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where it serves as a key precursor for pharmacophores and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for molecules targeting various disease pathways.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science Research: Serves as a building block for organic electronic materials, ligands for catalysts, and specialty polymers.
• Chemical Biology & Proteomics: Utilized as a scaffold or linker in the design of chemical probes and enzyme inhibitors for biological studies.
• Dye & Pigment Intermediate: Acts as a precursor in the synthesis of specialized heterocyclic dyes and colorants.

Basic Information

Product Name	(2-Phenyl-1,3-thiazol-4-yl)acetonitrile
CAS No.	16441-25-1
Molecular Formula	C11H8N2S
Molecular Weight	200.26 g/mol
Synonyms	4-Thiazoleacetonitrile, 2-phenyl-; 2-Phenyl-4-thiazoleacetonitrile; (2-Phenyl-4-thiazolyl)acetonitrile; 2-Phenylthiazole-4-acetonitrile; 4-(Cyanomethyl)-2-phenylthiazole; (2-Phenylthiazol-4-yl)acetonitrile; 2-Phenyl-1,3-thiazole-4-acetonitrile
EINECS	Contact for details

Quality Control

Our (2-Phenyl-1,3-thiazol-4-yl)acetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP and ISO standards ensures reliable supply for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.