Description

n-(2-Trimethylsiloxyethyl)Aniline is a specialized organosilicon compound featuring a reactive aniline moiety linked to a trimethylsiloxyethyl group. This unique structure makes it a valuable silyl-protected intermediate and building block in advanced organic synthesis. It is primarily utilized by manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and fine chemicals. Its properties are critical for processes requiring selective protection and functional group manipulation.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring protected amine functionalities.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where its silicon group aids in stability and bioavailability.
• Silicon Chemistry & Material Science: Serves as a precursor for modifying surfaces or creating hybrid organic-inorganic materials and silicone-based polymers.
• Fine Chemical Production: Employed in custom synthesis and research for creating complex molecules in laboratory and pilot-scale operations.
• Cross-coupling Reactions: Acts as a substrate in palladium-catalyzed and other metal-mediated coupling reactions to form new carbon-nitrogen bonds.

Basic Information

Product Name	n-(2-Trimethylsiloxyethyl)Aniline
CAS No.	16403-21-7
Molecular Formula	C11H19NOSi
Molecular Weight	209.36 g/mol
Synonyms	N-[2-(Trimethylsilyloxy)ethyl]aniline; 2-[(Trimethylsilyl)oxy]-N-phenylethanamine; Aniline, N-[2-(trimethylsilyl)oxy]ethyl]-; N-Phenylethanolamine trimethylsilyl ether; N-(2-Hydroxyethyl)aniline trimethylsilyl ether; TMS-O-ethyl aniline; (2-Anilinoethoxy)trimethylsilane
EINECS	Contact for details

Quality Control

Our n-(2-Trimethylsiloxyethyl)Aniline is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for critical synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.