Description

5-Ethoxy-1H-Indole-2-Carboxylic Acid Ethyl Ester is a high-purity, versatile indole derivative serving as a critical building block in advanced organic synthesis. Its value lies in its functionalized indole core, which is essential for constructing complex molecular architectures with specific biological activities. This intermediate is primarily needed by pharmaceutical R&D teams, agrochemical innovators, and fine chemical manufacturers developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in creating advanced crop protection agents and plant growth regulators due to its bioactive indole scaffold.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport or emissive layer materials in display and lighting technologies.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Biochemical Research: Utilized as a standard or probe in studying enzyme inhibition and receptor binding mechanisms.
• Fine Chemical Production: Acts as a versatile starting material for dyes, pigments, and other specialty chemicals requiring a functionalized indole structure.

Basic Information

Product Name	5-Ethoxy-1H-Indole-2-Carboxylic Acid Ethyl Ester
CAS No.	16382-17-5
Molecular Formula	C₁₃H₁₅NO₃
Molecular Weight	233.26 g/mol
Synonyms	Ethyl 5-ethoxy-1H-indole-2-carboxylate; 5-Ethoxyindole-2-carboxylic acid ethyl ester; 1H-Indole-2-carboxylic acid, 5-ethoxy-, ethyl ester; 2-Carbethoxy-5-ethoxyindole; 5-Ethoxy-2-ethoxycarbonylindole; Ethyl 5-ethoxy-2-indolecarboxylate; 16382-17-5; NSC 163467
EINECS	Contact for details

Quality Control

Our 5-Ethoxy-1H-Indole-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) documenting full specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.