Description

2-Bromo-1-Methylestra-1,3,5(10)-Triene-3,17β-Diol CAS NO 16373-36-7 is a brominated steroid derivative, specifically a modified estrane, that serves as a critical advanced intermediate in pharmaceutical research and development. Its value lies in its unique molecular structure, which provides a versatile scaffold for synthesizing novel steroid-based compounds with targeted biological activity. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those focused on developing new therapeutic agents, hormone analogs, and chemical probes for biological studies.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel steroid-based drugs and active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new therapeutic candidates.
• Hormone Analog Synthesis: Serves as a precursor for creating modified estrogens and other hormone receptor modulators.
• Biochemical Probes: Utilized in developing labeled or tagged compounds for studying steroid metabolism and receptor interactions.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for producing complex, high-value specialty chemicals.

Basic Information

Product Name	2-Bromo-1-Methylestra-1,3,5(10)-Triene-3,17β-Diol
CAS No.	16373-36-7
Molecular Formula	C19H25BrO2
Molecular Weight	365.31 g/mol
Synonyms	2-Bromo-1-methylestra-1,3,5(10)-triene-3,17β-diol; 2-Bromo-1-methylestradiol; 2-Bromo-1-methyl-3,17β-estradiol; 1-Methyl-2-bromoestra-1,3,5(10)-triene-3,17β-diol; 17β-Hydroxy-2-bromo-1-methylestra-1,3,5(10)-trien-3-ol; 2-Bromo-1-methyl-17β-estradiol
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-Methylestra-1,3,5(10)-Triene-3,17β-Diol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.