Description

1-Butylquinazolin-4(1H)-One is a specialized quinazolinone derivative, a heterocyclic compound of significant interest in advanced organic synthesis. Its core value lies in serving as a versatile and high-purity building block for the development of novel pharmacologically active molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of potential drug candidates targeting various therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs), especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the generation of compound libraries for high-throughput screening.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging the bioactive properties of the quinazolinone moiety.
• Organic Synthesis Building Block: Employed in complex multi-step organic syntheses to construct more elaborate heterocyclic systems for material science or chemical biology applications.
• Biochemical Tool Compound: Potential use in biochemical assays as a probe or inhibitor to study specific enzyme pathways and biological mechanisms.

Basic Information

Product Name	1-Butylquinazolin-4(1H)-One
CAS No.	16347-94-7
Molecular Formula	C₁₂H₁₄N₂O
Molecular Weight	202.25 g/mol
Synonyms	1-Butyl-4-quinazolinone; 1-Butyl-4(1H)-quinazolinone; 4(1H)-Quinazolinone, 1-butyl-; Quinazolin-4(1H)-one, 1-butyl-; 1-n-Butylquinazolin-4(1H)-one; 1-Butyl-1,4-dihydroquinazolin-4-one; 1-Butylquinazolin-4-ol
EINECS	Contact for details

Quality Control

Our 1-Butylquinazolin-4(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.