Description

1-(Aminomethyl)-3-Methylenecyclobutane 97% is a high-purity, functionalized cyclobutane derivative featuring both an aminomethyl and a methylene group. This unique bifunctional structure makes it a valuable and versatile building block in advanced organic synthesis, particularly for constructing complex, strained-ring systems. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those containing constrained, bioactive cyclobutane scaffolds.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the strained ring system can impart unique biological activity.
• Ligand and Catalyst Development: The primary amine functionality allows for its use in creating novel chelating ligands and organocatalysts for asymmetric synthesis.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for the production of specialty polymers with tailored thermal and mechanical properties.
• Chemical Research: A fundamental reagent in academic and industrial research for exploring new [2+2] cycloaddition reactions and ring-opening/expansion chemistry.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fragrance molecules, dyes, and other high-value specialty chemicals.

Basic Information

Product Name	1-(Aminomethyl)-3-Methylenecyclobutane 97%
CAS No.	16333-93-0
Molecular Formula	C6H11N
Molecular Weight	97.16 g/mol
Synonyms	3-Methylenecyclobutylmethylamine; (3-Methylenecyclobutyl)methanamine; 1-(Aminomethyl)-3-methylenecyclobutane; 3-Methylenecyclobutanemethylamine; Aminomethylmethylenecyclobutane; NSC 163333; 3-Methylen-cyclobutylmethylamin (German); 3-Méthylènecyclobutylméthylamine (French)
EINECS	Contact for details

Quality Control

Our 1-(Aminomethyl)-3-Methylenecyclobutane 97% is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure it meets the specified purity and identity criteria. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Due to its hygroscopic and easily oxidized nature, the container should be kept tightly sealed after each use to minimize exposure to moisture and air. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.