Description

Methyl 2,3-Dichloro-2,3,3-Trifluoropropionate is a high-purity fluorinated organic ester, serving as a versatile and critical building block in advanced chemical synthesis. Its unique structure, featuring both chlorine and fluorine substituents, makes it a valuable precursor for introducing trifluoromethyl and difluoromethylene groups into target molecules. This compound is essential for R&D and production chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in antiviral and anticancer drug discovery.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides, leveraging fluorine's ability to improve lipophilicity and biological activity.
• Advanced Material Precursor: Used in the development of specialty polymers, liquid crystals, and organic electronic materials requiring fluorinated segments.
• Organic Synthesis Reagent: Employed in nucleophilic substitution and coupling reactions to incorporate CF3 and CF2 groups into complex organic frameworks.
• Fluorine Chemistry Research: A standard reagent in academic and industrial laboratories for studying fluorination reactions and developing new synthetic methodologies.

Basic Information

Product Name	Methyl 2,3-Dichloro-2,3,3-Trifluoropropionate
CAS No.	16329-89-8
Molecular Formula	C4H3Cl2F3O2
Molecular Weight	228.97 g/mol
Synonyms	Methyl 2,3-dichloro-3,3,3-trifluoropropionate; 2,3-Dichloro-3,3,3-trifluoropropionic Acid Methyl Ester; Methyl 2,3-Dichloro-3,3,3-trifluoropropanoate; Propanoic acid, 2,3-dichloro-3,3,3-trifluoro-, methyl ester; Methyl α,β-Dichloro-β,β,β-trifluoropropionate
EINECS	Contact for details

Quality Control

Our Methyl 2,3-Dichloro-2,3,3-Trifluoropropionate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistent lot-to-lot performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its nature as a strong acid/organic solvent, ensure containers are kept tightly sealed to prevent moisture ingress and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.55 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.