Description

4-(1-Bromo-Ethyl)-Benzoic Acid Methyl Ester is a versatile brominated aromatic ester that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the reactive bromoethyl moiety, which enables efficient carbon-carbon bond formation and functional group transformations under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for constructing complex molecular scaffolds and active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in medicinal chemistry research for lead optimization.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the bromoethyl group is leveraged for alkylation reactions.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing specialized aromatic compounds used in electronic displays and organic light-emitting diodes.
• Polymer & Resin Modifier: Employed to introduce aromatic and bromine functionalities into polymer chains, enhancing flame retardancy and thermal stability.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create biaryl structures.
• Fine Chemical & Dye Intermediate: Utilized in the multi-step synthesis of complex dyes, pigments, and other high-value specialty chemicals.

Basic Information

Product Name	4-(1-Bromo-Ethyl)-Benzoic Acid Methyl Ester
CAS No.	16281-97-3
Molecular Formula	C10H11BrO2
Molecular Weight	243.10 g/mol
Synonyms	Methyl 4-(1-Bromoethyl)benzoate; Methyl 4-(α-Bromoethyl)benzoate; p-(1-Bromoethyl)benzoic Acid Methyl Ester; Benzoic acid, 4-(1-bromoethyl)-, methyl ester; 4-(α-Bromoethyl)benzoic Acid Methyl Ester; Methyl p-(1-bromoethyl)benzoate; 1-(4-(Methoxycarbonyl)phenyl)ethyl bromide
EINECS	Contact for details

Quality Control

Our 4-(1-Bromo-Ethyl)-Benzoic Acid Methyl Ester is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.