Description

4-Bromomethyl-Isophthalic Acid Dimethyl Ester is a high-purity, versatile brominated aromatic ester that serves as a critical synthetic intermediate. Its value lies in the reactive bromomethyl group, which enables efficient functionalization and chain extension in complex organic syntheses. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require a reliable building block for creating active pharmaceutical ingredients (APIs), liquid crystal polymers, and specialty polymers.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), particularly where aromatic ring functionalization is required.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators that incorporate brominated aromatic structures.
• Liquid Crystal & Polymer Chemistry: Serves as a monomer or precursor for synthesizing high-performance liquid crystal polymers (LCPs) and specialty polyesters with tailored thermal and mechanical properties.
• Organic Synthesis & Research: A versatile reagent for nucleophilic substitution reactions (SN2), facilitating the introduction of functional groups via the reactive bromomethyl site in academic and industrial R&D.
• Material Science: Employed in the development of advanced organic electronic materials, coatings, and adhesives requiring brominated aromatic components.
• Cross-coupling Reactions: Acts as a substrate in various metal-catalyzed cross-coupling reactions, such as Suzuki or Heck reactions, for constructing complex biaryl systems.

Basic Information

Product Name	4-Bromomethyl-Isophthalic Acid Dimethyl Ester
CAS No.	16281-94-0
Molecular Formula	C11H11BrO4
Molecular Weight	287.11 g/mol
Synonyms	Dimethyl 4-(Bromomethyl)isophthalate; 4-(Bromomethyl)isophthalic Acid Dimethyl Ester; 1,3-Benzenedicarboxylic Acid, 4-(Bromomethyl)-, Dimethyl Ester; Isophthalic Acid, 4-Bromomethyl-, Dimethyl Ester; 4-Bromomethyl-1,3-Benzenedicarboxylic Acid Dimethyl Ester; Dimethyl 4-Bromomethylisophthalate; 4-(Bromomethyl)benzene-1,3-dicarboxylic acid dimethyl ester
EINECS	Contact for details

Quality Control

Our 4-Bromomethyl-Isophthalic Acid Dimethyl Ester is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting critical parameters such as assay, impurity profile, and physical characteristics. Our commitment to reliable supply and traceable documentation supports your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in darkness. Keep the container tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.