Description

Morpholin-4-Ylphosphonochloridous Acid Methylester is a specialized organophosphorus compound that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring both a morpholine ring and a reactive phosphonochloridate ester group, makes it a versatile intermediate for introducing phosphorus-containing functionalities. This compound is essential for researchers and manufacturers in the agrochemical and pharmaceutical sectors who require precise molecular scaffolds for developing new active ingredients. Its controlled reactivity allows for the efficient construction of complex molecules with targeted biological or material properties.

Application

• Agrochemical Intermediate: Key precursor in the synthesis of novel insecticides, herbicides, and fungicides, particularly those with phosphonate or phosphoramidate moieties.
• Pharmaceutical Research: Used in medicinal chemistry for constructing potential drug candidates, especially protease inhibitors or other biologically active phosphorus analogs.
• Ligand Synthesis: Serves as a starting material for creating specialized phosphine-phosphite or related ligands used in asymmetric catalysis.
• Flame Retardant Development: Intermediate in the production of phosphorus-based flame retardants for polymers and materials.
• Chemical Biology Probes: Utilized to synthesize activity-based probes for studying enzyme mechanisms, particularly phosphatases and kinases.
• Polymer Modification: Agent for introducing phosphorus functional groups into polymer chains to alter material properties like adhesion or flame resistance.

Basic Information

Product Name	Morpholin-4-Ylphosphonochloridous Acid Methylester
CAS No.	16276-74-7
Molecular Formula	C5H11ClNO2P
Molecular Weight	183.57 g/mol
Synonyms	Methyl Morpholinochlorophosphite; Methyl N-Morpholinylchlorophosphonite; Morpholine, 4-(chloromethoxyphosphinyl)-; 4-Morpholinecarbonchloridous Acid Methyl Ester; Chloro(morpholino)methoxyphosphine; Morpholin-4-ylphosphonochloridic Acid Methyl Ester; Phosphorochloridous Acid, Morpholino-, Methyl Ester
EINECS	Contact for details

Quality Control

Every batch of Morpholin-4-Ylphosphonochloridous Acid Methylester is produced and tested under strict quality management protocols to ensure consistency and purity for demanding synthetic applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.