Description

2-Chloro-1H-Imidazole is a versatile halogenated heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its reactive chloro substituent, which enables efficient functionalization to create complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates, including antifungal, antiviral, and anticancer agents.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides, leveraging its heterocyclic core for biological activity.
• Ligand and Catalyst Preparation: Serves as a starting material for N-heterocyclic carbene (NHC) ligands and other organocatalysts used in asymmetric synthesis.
• Material Science: Employed in the development of specialty polymers, ionic liquids, and advanced organic electronic materials.
• Custom Synthesis & Research: A fundamental reagent for medicinal chemistry research and the construction of imidazole-based compound libraries.

Basic Information

Product Name	2-Chloro-1H-Imidazole
CAS No.	16265-04-6
Molecular Formula	C3H3ClN2
Molecular Weight	102.52 g/mol
Synonyms	2-Chloroimidazole; 2-Chloro-1H-imidazole; 2-Chloroimidazole (HCl); Imidazole, 2-chloro-; 2-Cl-Imidazole; 2-Chloroimidazole Hydrochloride; 2-Chloro-1H-imidazole hydrochloride; 2-Chloroimidazole, free base
EINECS	Contact for details

Quality Control

Our 2-Chloro-1H-Imidazole is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.