Description

(3S)-2,3,4,5,6,7-Hexahydro-7,7,8-Trimethyl-1H-3Aα,6α-Methanoazulene-3α-Carboxylic Acid is a high-purity, stereochemically defined carboxylic acid derivative of a complex methanoazulene structure. This compound serves as a critical chiral intermediate and building block in advanced organic synthesis, where its unique fused ring system is highly valuable. It is primarily required by pharmaceutical R&D and fine chemical manufacturers for the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new therapeutic agents, particularly in areas requiring complex polycyclic frameworks.
• Asymmetric Synthesis: Utilized as a building block in catalytic asymmetric reactions to construct molecules with specific three-dimensional configurations.
• Fragrance & Flavor Chemistry: Serves as a precursor for synthesizing novel aroma chemicals with unique olfactive properties derived from its azulene-related structure.
• Material Science Research: Investigated as a monomer or functional additive for creating specialized polymers with tailored thermal or optical characteristics.
• Agrochemical Development: Potential intermediate in the synthesis of advanced crop protection agents with novel modes of action.
• Academic & Industrial R&D: Used in methodological studies and process chemistry for developing new synthetic routes to complex natural product analogs.

Basic Information

Product Name	(3S)-2,3,4,5,6,7-Hexahydro-7,7,8-Trimethyl-1H-3Aα,6α-Methanoazulene-3α-Carboxylic Acid
CAS No.	16202-79-2
Molecular Formula	C₁₅H₂₂O₂
Molecular Weight	234.33 g/mol
Synonyms	(3S)-3a,4,5,6,7,8-Hexahydro-3a,5,5,8a-tetramethyl-1H-3a,6-methanoazulen-3-carboxylic acid; (3S)-3a,4,5,6,7,8-Hexahydro-3a,5,5,8a-tetramethyl-3a,6-methanoazulen-3-carboxylic acid; (3S)-2,3,4,5,6,7-Hexahydro-7,7,8-trimethyl-1H-3a,6-methanoazulen-3a-carboxylic acid; (3S)-3a,4,5,6,7,8-Hexahydro-3a,5,5,8a-tetramethyl-3a,6-methanoazulene-3-carboxylic acid; (3S)-3a,4,5,6,7,8-Hexahydro-3a,5,5,8a-tetramethyl-3a,6-methanoazulen-3-carboxylic acid; (3S)-3a,4,5,6,7,8-Hexahydro-3a,5,5,8a-tetramethyl-3a,6-methanoazulen-3-carboxylic acid; (3S)-3a,4,5,6,7,8-Hexahydro-3a,5,5,8a-tetramethyl-3a,6-methanoazulen-3-carboxylic acid
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Quality Control

Our production of (3S)-2,3,4,5,6,7-Hexahydro-7,7,8-Trimethyl-1H-3Aα,6α-Methanoazulene-3α-Carboxylic Acid adheres to a strict quality management system. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for pharmaceutical and fine chemical applications. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.