Description

[S,(+)]-2,2,3-Trimethyl-3α-(4-Methylphenyl)Cyclopentanone is a high-purity, optically active chiral ketone of significant interest in advanced organic synthesis. This compound matters as a versatile and valuable chiral building block for the creation of complex molecules with specific stereochemistry. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fragrance industries for the synthesis of active ingredients and specialty intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in areas requiring specific enantiomeric control.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure pesticides and herbicides, where biological activity is often stereospecific.
• Fragrance and Flavor Chemistry: Serves as a precursor for high-value aroma chemicals and odorants, leveraging its complex, substituted cyclopentanone structure.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in academic and industrial research focused on developing new chiral catalysts and synthetic methodologies.
• Fine Chemical Manufacturing: Utilized in custom synthesis and contract manufacturing for producing specialized, high-value chemical entities for various industrial applications.
• Material Science Research: Potential building block for chiral polymers or advanced organic materials with specific optical properties.

Basic Information

Item	Details
Product Name	[S,(+)]-2,2,3-Trimethyl-3α-(4-Methylphenyl)Cyclopentanone
CAS No.	16196-32-0
Molecular Formula	C15H20O
Molecular Weight	216.32 g/mol
Synonyms	(+)-(S)-2,2,3-Trimethyl-3-(4-methylphenyl)cyclopentanone; (S)-(+)-2,2,3-Trimethyl-3-(p-tolyl)cyclopentanone; (3S)-2,2,3-Trimethyl-3-(4-methylphenyl)cyclopentan-1-one; (+)-2,2,3-Trimethyl-3-(4-methylphenyl)cyclopentanone; (S)-2,2,3-Trimethyl-3-(p-tolyl)cyclopentanone; p-Methyl-α-santalol ketone (related structure); Chiral Trimethyl-Methylphenyl Cyclopentanone
EINECS	Contact for details

Quality Control

Our production of [S,(+)]-2,2,3-Trimethyl-3α-(4-Methylphenyl)Cyclopentanone adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including chiral purity analysis (HPLC/GC), to ensure high enantiomeric excess (ee) and chemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed specifications for identity, purity, and impurities are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Specific Rotation [α]	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.