Description

1-Aminocyclopentane Carbonitrile, Hcl is a versatile and high-purity organic building block essential for advanced chemical synthesis. This compound matters as a key chiral intermediate, enabling the construction of complex molecular architectures with high stereochemical control. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs), agrochemicals, and novel materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where specific stereochemistry is required for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetic Research: Employed in medicinal chemistry for designing and synthesizing peptide analogs and conformationally restricted scaffolds.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.
• Material Science: Potential monomer or precursor for specialty polymers and functional materials requiring cyclopentane-based structures.

Basic Information

Product Name	1-Aminocyclopentane Carbonitrile, Hcl
CAS No.	16195-83-8
Molecular Formula	C6H11N2•HCl
Molecular Weight	146.63 g/mol (Free base: 110.16 g/mol)
Synonyms	1-Aminocyclopentanecarbonitrile Hydrochloride; (1-Cyano-1-cyclopentyl)amine Hydrochloride; 1-Cyano-1-cyclopentanamine Hydrochloride; 1-Amino-1-cyclopentanecarbonitrile Hydrochloride; Cyclopentanecarbonitrile, 1-amino-, hydrochloride; 1-Aminocyclopentyl cyanide hydrochloride; Aminocyclopentanecarbonitrile HCl; 1-Cyclopentylamino-1-cyanomethane hydrochloride
EINECS	Contact for details

Quality Control

Our 1-Aminocyclopentane Carbonitrile, Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.