Description

2'-(Trifluoromethyl)Propiophenone is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in the strategic introduction of the trifluoromethyl group, a key moiety known to dramatically alter the physicochemical and metabolic properties of target molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries who require high-purity intermediates for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the CF3 group enhances bioavailability and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Fluorine Chemistry: A valuable substrate for studying novel fluorination reactions and developing new methodologies in organofluorine chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific fluorinated aromatic scaffolds.

Basic Information

Product Name	2'-(Trifluoromethyl)Propiophenone
CAS No.	16185-96-9
Molecular Formula	C10H9F3O
Molecular Weight	202.17 g/mol
Synonyms	1-Propanone, 1-[2-(trifluoromethyl)phenyl]-; 2-(Trifluoromethyl)propiophenone; α-Methyl-2-(trifluoromethyl)acetophenone; 2-Trifluoromethylpropiophenone; 1-(2-Trifluoromethylphenyl)propan-1-one; 2'-Trifluoromethylpropiophenone; Propiophenone, 2'-(trifluoromethyl)-; 2-(Trifluoromethyl)phenyl ethyl ketone
EINECS	Contact for details

Quality Control

Our 2'-(Trifluoromethyl)Propiophenone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.