Description

Orthoformic Acid, Cyclic Ethylene 2-Chloroethyl Ester (8Ci) is a specialized organic ester compound, identified by CAS number 16162-30-4. This chemical serves as a valuable protected formate reagent and versatile synthetic intermediate in advanced organic synthesis. It is primarily needed by pharmaceutical, agrochemical, and fine chemical R&D and manufacturing sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing protected formyl or alkoxycarbonyl groups.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides requiring specific ester functionalities.
• Fine Chemical Manufacturing: Serves as a precursor for dyes, pigments, flavors, and fragrances where its cyclic ester structure is advantageous.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the development of specialty polymers with tailored properties.
• Organic Synthesis Reagent: Employed in laboratories for transesterification reactions and as a protecting group for acids and alcohols.
• Chemical Research & Development: A valuable tool for medicinal chemistry and process chemistry in exploring new synthetic pathways.

Basic Information

Product Name	Orthoformic Acid, Cyclic Ethylene 2-Chloroethyl Ester (8Ci)
CAS No.	16162-30-4
Molecular Formula	C5H7ClO3
Molecular Weight	150.56 g/mol
Synonyms	2-Chloroethyl Orthoformate, Cyclic Ethylene Ester; 2-Chloroethyl Formate, Cyclic Dimer; 1,3-Dioxolane-2-methanol, 2-(chloromethyl)-; Ethylene Chlorohydrin Orthoformate; Orthoformic Acid 2-Chloroethyl Ester Cyclic; (2-Chloroethoxy)methanol Formal; 2-(Chloromethyl)-1,3-dioxolan-4-ylmethanol; 16162-30-4 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our Orthoformic Acid, Cyclic Ethylene 2-Chloroethyl Ester (8Ci) is produced under a stringent quality management system. Each batch undergoes rigorous analytical testing to ensure high purity, consistency, and traceability, meeting the exacting standards required for synthesis and industrial applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids, bases, and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	≤ 2.0% total
Density (20°C)	~1.30 g/mL
Refractive Index (20°C)	~1.445

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.