Description

5α-Cholestane-3-One Dimethyl Acetal is a high-purity steroidal intermediate of significant importance in advanced organic synthesis. This compound serves as a critical building block for the preparation of more complex steroid derivatives and analogs used in pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, reference standards, and biochemical probes.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel steroid-based drug candidates and active pharmaceutical ingredients (APIs).
• Reference Standard: Used as an analytical standard in chromatography (HPLC, GC) for method development, validation, and quality control in steroid analysis.
• Biochemical Research: Employed in metabolic pathway studies and as a starting material for synthesizing labeled compounds (e.g., deuterated or C13-labeled steroids) for tracer studies.
• Organic Synthesis: Serves as a versatile chiral building block for constructing complex natural products and steroidal frameworks in academic and industrial R&D laboratories.

Basic Information

Product Name	5α-Cholestane-3-One Dimethyl Acetal
CAS No.	16159-03-8
Molecular Formula	C₂₉H₅₂O₂
Molecular Weight	432.73 g/mol
Synonyms	5α-Cholestan-3-one dimethyl acetal; 3,3-Dimethoxy-5α-cholestane; Cholestane-3-one dimethyl acetal; 5α-Cholestane-3β-ol methyl ether (related); 3-Keto-5α-cholestane dimethyl acetal
EINECS	Contact for details

Quality Control

Our 5α-Cholestane-3-One Dimethyl Acetal is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as identity, purity, and impurity profile. We support compliance with cGMP guidelines for pharmaceutical intermediates, and specifications can be aligned with client-specific requirements for research or development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.