Description

Trimethyl Methoxyphosphonoacetate is a high-purity organophosphorus compound with the CAS number 16141-78-9, serving as a versatile and critical building block in advanced chemical synthesis. Its unique structure, featuring both phosphonate and ester functionalities, makes it an essential reagent for constructing complex molecular architectures. This product is primarily targeted at research and development laboratories, pharmaceutical intermediates manufacturers, and agrochemical producers who require reliable, high-quality synthetic precursors.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing phosphonate or phosphate ester groups.
• Agrochemical Synthesis: Used in the production of advanced herbicides, plant growth regulators, and other crop protection agents where its phosphonate moiety is incorporated.
• Chemical Research & Development: Serves as a fundamental reagent in organic synthesis for Horner-Wadsworth-Emmons (HWE) olefination reactions and other carbon-carbon bond forming processes.
• Ligand and Catalyst Preparation: Employed in the development of specialized phosphonate-based ligands for metal catalysis and coordination chemistry.
• Material Science Precursor: Utilized in the synthesis of functionalized polymers and advanced materials with specific surface properties.
• Flame Retardant Synthon: Acts as a building block for creating phosphorus-containing flame retardant additives for polymers and textiles.

Basic Information

Product Name	Trimethyl Methoxyphosphonoacetate
CAS No.	16141-78-9
Molecular Formula	C6H13O5P
Molecular Weight	196.14 g/mol
Synonyms	Methoxy(trimethoxyphosphinyl)acetate; Trimethyl (methoxyphosphinyl)acetate; Acetic acid, 2-methoxy-2-oxo-, trimethyl ester; (Methoxyphosphinyl)acetic acid trimethyl ester; Dimethyl methoxyphosphonoacetate (common misnomer); Phosphonoacetic acid, methoxy-, trimethyl ester; TM-MPA
EINECS	Contact for details

Quality Control

Every batch of Trimethyl Methoxyphosphonoacetate is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including chromatography and spectroscopy, to ensure compliance with exacting purity standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container must be kept tightly sealed in a dry environment to minimize moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.