Description

3-Bromo-1-Methyl-5-Nitro-1H-Pyridin-2-One is a versatile halogenated and nitrated pyridinone derivative, serving as a critical building block in advanced organic synthesis. Its unique structure makes it a valuable intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromo and nitro functionalities into heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to create complex molecular architectures.
• Material Science Research: Potential monomer or functionalizing agent in the development of specialty polymers and advanced organic electronic materials.
• Chemical Research & Development: Serves as a standard or reagent in methodological studies and for exploring new chemical transformations involving halogenated nitropyridines.

Basic Information

Product Name	3-Bromo-1-Methyl-5-Nitro-1H-Pyridin-2-One
CAS No.	16098-21-8
Molecular Formula	C6H5BrN2O3
Molecular Weight	233.02 g/mol
Synonyms	3-Bromo-1-methyl-5-nitro-2(1H)-pyridinone; 3-Bromo-1-methyl-5-nitropyridin-2(1H)-one; 1-Methyl-3-bromo-5-nitro-2(1H)-pyridinone; 2(1H)-Pyridinone, 3-bromo-1-methyl-5-nitro-; 3-Bromo-1-methyl-5-nitro-1H-pyridin-2-one; 16098-21-8
EINECS	Contact for details

Quality Control

Our 3-Bromo-1-Methyl-5-Nitro-1H-Pyridin-2-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.