Description

(-)-Menthyl Chloride CAS NO 16052-42-9 is a chiral organic chloride derivative of menthol, serving as a versatile and valuable intermediate in fine chemical synthesis. Its primary commercial value lies in its role as a key building block for the production of high-value flavor and fragrance compounds, agrochemicals, and pharmaceutical ingredients. This product is essential for manufacturers and R&D laboratories in the flavor & fragrance, agrochemical, and pharmaceutical industries seeking a reliable source of a high-purity chiral synthon.

Application

• Flavor and Fragrance (F&F) Industry: A critical chiral intermediate for synthesizing high-value menthol derivatives, cooling agents, and specialty aroma chemicals.
• Agrochemical Synthesis: Used as a building block in the production of certain pesticides and herbicides, leveraging its chiral center for biological activity.
• Pharmaceutical Intermediates: Serves as a key starting material or intermediate in the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Organic Synthesis & Research: Employed in academic and industrial R&D for nucleophilic substitution reactions and as a precursor to other menthyl-based reagents.
• Specialty Chemical Manufacturing: Used in the production of catalysts, ligands, and other performance chemicals where the bulky menthyl group influences reactivity or selectivity.

Basic Information

Product Name	(-)-Menthyl Chloride
CAS No.	16052-42-9
Molecular Formula	C10H19Cl
Molecular Weight	174.71 g/mol
Synonyms	(-)-Menthyl chloride; (1R,2S,5R)-2-Chloro-1-isopropyl-4-methylcyclohexane; L-Menthyl chloride; (1R,2S,5R)-(-)-Menthyl chloride; (1R,2S,5R)-2-Chloro-1-isopropyl-4-methylcyclohexane; Chloromenthane; 2-Chloro-1-isopropyl-4-methylcyclohexane (stereospecific)
EINECS	240-179-4

Quality Control

Our (-)-Menthyl Chloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by GC or HPLC, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability, although the product is stable at room temperature for shorter periods. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Chiral Purity (GC/HPLC)	≥ 99.0% (1R,2S,5R)
Specific Rotation [α]20/D	-25° to -30° (c=1 in CHCl3)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.