Description

D,L-n-Acetyl-3-(3,4-Dimethoxyphenyl)-2-Methyl-Alanine Ethyl Ester is a high-purity, non-natural amino acid derivative with a complex chiral center, serving as a critical chiral building block and synthetic intermediate. This compound matters for its role in enabling the synthesis of sophisticated, biologically active molecules where precise stereochemistry is paramount. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for neurological and cardiovascular targets, as well as by fine chemical manufacturers producing advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, especially for central nervous system (CNS) and cardiovascular diseases.
• Peptidomimetics Research: Used in the design and synthesis of peptide analogs and mimetics to enhance metabolic stability and bioavailability.
• Asymmetric Synthesis: Serves as a starting material or resolving agent in asymmetric catalytic processes to introduce chiral complexity.
• Chemical Biology Probes: Utilized in the creation of labeled or modified amino acid derivatives for studying enzyme mechanisms and protein interactions.
• Fine Chemical Production: An advanced intermediate for the commercial-scale manufacture of specialty chemicals and high-value agrochemicals.
• Academic & Industrial R&D: Employed in methodological studies and process chemistry optimization within organic synthesis laboratories.

Basic Information

Product Name	D,L-n-Acetyl-3-(3,4-Dimethoxyphenyl)-2-Methyl-Alanine Ethyl Ester
CAS No.	16024-52-5
Molecular Formula	C₁₆H₂₃NO₅
Molecular Weight	309.36 g/mol
Synonyms	Ethyl 2-Acetamido-3-(3,4-dimethoxyphenyl)-2-methylpropanoate; 2-Acetamido-3-(3,4-dimethoxyphenyl)-2-methylpropanoic Acid Ethyl Ester; DL-3-(3,4-Dimethoxyphenyl)-2-methylalanine N-acetyl ethyl ester; N-Acetyl-3-(3,4-dimethoxyphenyl)-2-methyl-DL-alanine ethyl ester; Ac-D,L-3-(3,4-Dimethoxyphenyl)-2-methyl-Ala-OEt; (RS)-2-Acetamido-3-(3,4-dimethoxyphenyl)-2-methylpropanoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our D,L-n-Acetyl-3-(3,4-Dimethoxyphenyl)-2-Methyl-Alanine Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for pharmaceutical research and fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	DL-mixture (specified ratio available)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.