Description

1-(4-Methylphenyl)-1-Propyne-3-Ol is a specialized organic compound featuring a terminal alkyne and a hydroxyl group on a propargylic carbon attached to a p-tolyl ring. This unique structure makes it a valuable versatile building block in advanced organic synthesis, particularly for constructing complex molecular architectures. It is primarily utilized by pharmaceutical, agrochemical, and advanced materials research sectors for applications requiring precise molecular control and functional group diversity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially those containing chiral centers or complex heterocyclic systems.
• Agrochemical Synthesis: Used in the research and production of novel pesticides, herbicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis, such as cross-coupling reactions.
• Material Science Research: Employed in the synthesis of monomers for specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized in click chemistry applications (e.g., CuAAC reactions) for bioconjugation and labeling due to its terminal alkyne functionality.
• Fine Chemical Production: Acts as a building block for fragrances, flavors, and other high-value specialty chemicals.

Basic Information

Product Name	1-(4-Methylphenyl)-1-Propyne-3-Ol
CAS No.	16017-24-6
Molecular Formula	C10H10O
Molecular Weight	146.19 g/mol
Synonyms	3-(p-Tolyl)-2-propyn-1-ol; 1-(p-Tolyl)-2-propyn-1-ol; 3-(4-Methylphenyl)prop-2-yn-1-ol; 4-Methylphenylpropargyl alcohol; p-Tolylpropargyl alcohol; p-Methylphenylpropargyl alcohol; 1-(4-Methylphenyl)-2-propyn-1-ol
EINECS	Contact for details

Quality Control

Our 1-(4-Methylphenyl)-1-Propyne-3-Ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to ensure full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, acids, and bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥97.0% (Typical 98-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.