Description

2-Chloro-5-Trifluoromethylbenzyl Chloride is a versatile and highly reactive benzyl halide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the trifluoromethyl and chloro substituents, which impart unique electronic and steric properties to target molecules, enhancing their biological activity and physicochemical stability. This intermediate is essential for researchers and manufacturers in the agrochemical and pharmaceutical industries, particularly for developing novel active ingredients and complex fine chemicals.

Application

• Agrochemical Intermediate: A key precursor for the synthesis of modern herbicides, fungicides, and insecticides, where the trifluoromethyl group improves lipophilicity and metabolic stability.
• Pharmaceutical Building Block: Used in constructing bioactive molecules and active pharmaceutical ingredients (APIs), especially in medicinal chemistry for lead optimization.
• Liquid Crystal & OLED Material Synthesis: Employed in the production of advanced electronic materials and functional dyes due to its ability to modify molecular polarity and conjugation.
• Polymer & Resin Modification: Acts as a functional monomer or cross-linking agent to introduce specific properties into specialty polymers.
• General Organic Synthesis: A versatile reagent for introducing the 2-chloro-5-trifluoromethylbenzyl moiety into various molecular frameworks via nucleophilic substitution or coupling reactions.

Basic Information

Product Name	2-Chloro-5-Trifluoromethylbenzyl Chloride
CAS No.	15996-78-8
Molecular Formula	C8H5Cl2F3
Molecular Weight	229.03 g/mol
Synonyms	α,2-Dichloro-α-(trifluoromethyl)toluene; 1-(Chloromethyl)-2-chloro-5-(trifluoromethyl)benzene; 2-Chloro-α-(chloromethyl)-α,α,α-trifluorotoluene; 2-Chloro-5-trifluoromethylbenzyl chloride; 2-Chloro-α,α,α-trifluoro-p-tolyl chloride; (2-Chloro-5-(trifluoromethyl)phenyl)methyl chloride; Benzene, 1-(chloromethyl)-2-chloro-5-(trifluoromethyl)-; p-Chloro-α,α,α-trifluoro-o-tolyl chloride
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Trifluoromethylbenzyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability. The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.