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(1R,2S)-1,2-Dichloro-1,2-Diphenylethane CAS NO 15951-99-2
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CAS No.:15951-99-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(1R,2S)-1,2-Dichloro-1,2-Diphenylethane is a high-purity chiral organic compound of significant interest in advanced chemical synthesis. This stereospecific isomer serves as a critical chiral building block and intermediate for the production of complex, optically active molecules. It is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical producers requiring precise stereochemistry in their processes.
Application
- Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and cardiovascular diseases.
- Catalyst and Ligand Synthesis: Used in the preparation of chiral ligands for transition metal catalysts, which are vital for enantioselective hydrogenation and cross-coupling reactions.
- Advanced Material Research: Serves as a monomer or precursor in the development of chiral polymers and liquid crystals with specific optical properties.
- Agrochemical Development: Employed in the synthesis of chiral pesticides and herbicides where biological activity is stereospecific.
- Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry, including studies on stereoselective reactions and mechanistic pathways.
Basic Information
| Item | Detail |
|---|---|
| Product Name | (1R,2S)-1,2-Dichloro-1,2-Diphenylethane |
| CAS No. | 15951-99-2 |
| Molecular Formula | C14H12Cl2 |
| Molecular Weight | 251.15 g/mol |
| Synonyms | (1R,2S)-1,2-Dichloro-1,2-diphenylethane; (R,S)-1,2-Dichloro-1,2-diphenylethane; meso-1,2-Dichloro-1,2-diphenylethane; (1R,2S)-1,2-Dichlorostilbene; meso-Stilbene dichloride; 1,2-Dichloro-1,2-diphenylethane (meso-form); NSC 406913 |
| EINECS | Contact for details |
Quality Control
Our (1R,2S)-1,2-Dichloro-1,2-Diphenylethane is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Chiral Purity (Enantiomeric Excess) | ≥ 99.0% ee |
| Melting Point | 169 - 173 °C |
| Heavy Metals | ≤ 20 ppm |
| Residual Solvents (GC) | Complies with ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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