Description

trans-3-Methylamino-Cyclohexanol CAS NO 15942-10-6 is a chiral amino alcohol derivative of cyclohexane, serving as a versatile and valuable building block in advanced organic synthesis. Its structural features, combining a secondary amine with a hydroxyl group in a defined stereochemical configuration, make it a critical intermediate for constructing complex molecules with high stereochemical purity. This compound is essential for research and development chemists and process engineers in the pharmaceutical and fine chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and chiral ligands.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, including central nervous system (CNS) agents and receptor modulators.
• Asymmetric Catalyst Ligand: Used in the preparation of chiral ligands for metal-catalyzed asymmetric reactions, such as hydrogenation and addition reactions.
• Agrochemical Synthesis: Intermediate in the production of advanced, stereospecific pesticides and herbicides.
• Fine Chemical Building Block: Employed in custom synthesis and contract manufacturing for specialty chemicals requiring a defined amino alcohol moiety.
• Research & Development: Serves as a standard or starting material in academic and industrial R&D for methodological studies in organic and medicinal chemistry.

Basic Information

Product Name	trans-3-Methylamino-Cyclohexanol
CAS No.	15942-10-6
Molecular Formula	C7H15NO
Molecular Weight	129.20 g/mol
Synonyms	trans-3-(Methylamino)cyclohexanol; (1R,3R)-3-(Methylamino)cyclohexanol; (1S,3S)-3-(Methylamino)cyclohexanol; 3-Methylaminocyclohexanol; 3-(N-Methylamino)cyclohexanol; Cyclohexanol, 3-(methylamino)-, trans-; 15942-10-6
EINECS	Contact for details

Quality Control

Our trans-3-Methylamino-Cyclohexanol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles. We support compliance with cGMP, ICH guidelines, and relevant pharmacopeial standards as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (trans isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.