Description

1,8-Naphthyridin-2(8H)-One is a versatile nitrogen-containing heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique fused-ring structure makes it a valuable intermediate for developing novel pharmaceuticals and functional materials. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to create innovative products with specific biological or electronic properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various drug candidates, particularly those targeting infectious diseases, inflammation, and central nervous system disorders.
• Agrochemical Research: Used in developing new active ingredients for herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold.
• Material Science: Building block for creating organic semiconductors, light-emitting materials (OLEDs), and advanced polymers with specific electronic properties.
• Coordination Chemistry: Acts as a ligand for metal complexes in catalysis and materials chemistry due to its nitrogen donor atoms.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and enzyme mechanisms.
• Academic & Industrial R&D: Fundamental scaffold for medicinal chemistry programs and discovery research across multiple sectors.

Basic Information

Product Name	1,8-Naphthyridin-2(8H)-One
CAS No.	15936-09-1
Molecular Formula	C8H6N2O
Molecular Weight	146.15 g/mol
Synonyms	1,8-Naphthyridin-2(1H)-one; 2(1H)-1,8-Naphthyridinone; 1,8-Naphthyridin-2-ol; 2-Hydroxy-1,8-naphthyridine; 1H-1,8-Naphthyridin-2-one; 8H-1,8-Naphthyridin-2-one; 1,8-Naphthyridin-2-one
EINECS	Contact for details

Quality Control

Our 1,8-Naphthyridin-2(8H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and residual solvent analysis. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.