Description

S-tert-Butyl Acetothioacetate is a versatile sulfur-containing organic compound that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring both a thioester and a tert-butyl group, makes it a valuable reagent for introducing protected thiol functionalities and constructing complex heterocycles. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing sulfur heterocycles or requiring thiol protection/deprotection strategies.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where the acetothioacetate moiety contributes to biological activity.
• Fine Chemical Production: Serves as a precursor for various specialty chemicals, including ligands for catalysis, flavors, and fragrances.
• Polymer Chemistry: Employed in the synthesis of functional monomers and polymers with specific sulfur-based properties.
• Organic Synthesis Reagent: A valuable reagent for Claisen-type condensations and the preparation of β-keto thioesters, which are pivotal in multi-step synthetic routes.
• Research & Development: Utilized in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel molecular architectures.

Basic Information

Product Name	S-tert-Butyl Acetothioacetate
CAS No.	15925-47-0
Molecular Formula	C8H14O2S
Molecular Weight	174.26 g/mol
Synonyms	Acetoacetic Acid tert-Butyl Thioester; 3-Oxobutanoic Acid S-tert-Butyl Ester; tert-Butyl 3-Oxobutanethioate; S-tert-Butyl 3-Oxobutanethioate; Acetylthioacetic Acid tert-Butyl Ester; Butanoic acid, 3-oxo-, S-(1,1-dimethylethyl) ester; TBAA
EINECS	Contact for details

Quality Control

Our S-tert-Butyl Acetothioacetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.