Description

2-[5-Tetrazolyl]Phenylboronicacid is a specialized boronic acid derivative featuring a tetrazole functional group, making it a valuable bifunctional building block in synthetic chemistry. This compound is particularly significant for its role in facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for forming carbon-carbon bonds. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, as well as in materials science for creating advanced organic frameworks and polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing biphenyl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science: Serves as a monomer or cross-linking agent in the production of advanced organic polymers, covalent organic frameworks (COFs), and liquid crystals.
• Chemical Biology & Proteomics: Employed as a versatile handle in bioconjugation strategies and for the development of enzyme inhibitors or molecular probes.
• Catalyst Ligand Development: The tetrazole moiety can act as a coordinating group in the design of novel metal-organic catalysts.
• Academic & Industrial R&D: A fundamental reagent for methodological development in cross-coupling chemistry and heterocycle synthesis.

Basic Information

Product Name	2-[5-Tetrazolyl]Phenylboronicacid
CAS No.	15884-01-8
Molecular Formula	C8H7BN4O2
Molecular Weight	202.98 g/mol
Synonyms	2-(1H-Tetrazol-5-yl)benzeneboronic acid; (2-(1H-Tetrazol-5-yl)phenyl)boronic acid; 2-(1H-Tetrazol-5-yl)phenylboronic acid; 2-(2H-Tetrazol-5-yl)phenylboronic acid; 2-(Tetrazol-5-yl)phenylboronic acid; 2-Tetrazol-5-ylbenzeneboronic acid; 5-(2-Boronophenyl)-1H-tetrazole; 2-(1H-1,2,3,4-Tetrazol-5-yl)benzeneboronic acid
EINECS	Contact for details

Quality Control

Our 2-[5-Tetrazolyl]Phenylboronicacid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.