Description

2-Hydroxy-3-Methyl-2-Phenylbutanoic Acid is a chiral α-hydroxy acid derivative that serves as a valuable intermediate in advanced organic synthesis. Its structure, featuring both a hydroxyl and a carboxylic acid group on a tertiary carbon, makes it a versatile building block for constructing complex molecules with defined stereochemistry. This compound is primarily sought by the pharmaceutical and fine chemical industries for applications in asymmetric synthesis and as a precursor for active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and development of new therapeutic agents and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used as a building block or auxiliary in catalytic and stoichiometric asymmetric reactions to induce chirality.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, agrochemicals, and performance materials.
• Ligand and Catalyst Development: Serves as a precursor for novel chiral ligands and organocatalysts used in enantioselective transformations.
• Academic and R&D: Utilized in chemical research for methodological studies and the synthesis of novel organic compounds.

Basic Information

Product Name	2-Hydroxy-3-Methyl-2-Phenylbutanoic Acid
CAS No.	15879-60-4
Molecular Formula	C11H14O3
Molecular Weight	194.23 g/mol
Synonyms	2-Phenyl-2-hydroxy-3-methylbutyric acid; α-Hydroxy-α-phenylisovaleric acid; 3-Methyl-2-phenyl-2-hydroxybutanoic acid; 2-Hydroxy-2-phenyl-3-methylbutyric acid; 2-Phenyl-2-hydroxy-3-methylbutanoic acid; DL-2-Hydroxy-3-methyl-2-phenylbutyric acid; (±)-2-Hydroxy-3-methyl-2-phenylbutanoic acid
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-3-Methyl-2-Phenylbutanoic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay, chiral purity (if applicable), and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.